Lecapon-Mepha Lactab 150mg/37.5mg/200mg 30 pcs

What is Lecapon-Mepha and when is it used?

As prescribed by your doctor.

Lecapon-Mepha is used to treat patients with Parkinson's Disease used that suffer from certain symptoms (fluctuating motor symptoms, so-called end dose or «on-off» symptoms). Lecapon-Mepha is used when the symptoms have not been adequately stabilized under previous therapy with one or two active ingredients.

Lecapon-Mepha is a combination of three active substances in one lactab. Every Lactab Lecapon-Mepha contains levodopa as a component that works against Parkinson's disease. In addition, each lactab contains carbidopa and entacapone. These improve the effect of relieving the Parkinson's symptoms of levodopa.

When should Lecapon-Mepha not be taken?

Lecapon-Mepha must not be taken if:

• you are hypersensitive to the active ingredients levodopa, carbidopa, entacapone or one of the other ingredients of Lecapon-Mepha.
• You have liver disease.
• You suffer from increased intraocular pressure due to glaucoma (glaucoma).
• You have suffer from pheochromocytoma (a tumor of the adrenal gland), as this can increase the risk of severe increases in blood pressure.
• You are taking certain antidepressants (selective MAO-A and MAO-B inhibitors in combination or non-selective MAO- Inhibitors).
• You have developed neuroleptic malignant syndrome (NMS) and / or non-traumatic rhabdomyolysis (a rare type of muscle disorder) ten is.
• You have or have a melanoma. or have a suspicious, previously undiagnosed skin lesion.
• You are under 18 years of age.

When should you be careful when taking Lecapon-Mepha?

Take care when taking Lecapon-Mepha:

• If you have had a heart attack or any other disease of the cardiovascular system or the lungs, bronchial asthma, a kidney or an endocrine disorder, or under suffer from a special type of involuntary movement (called extrapyramidal disorder), have had a stomach ulcer or seizure, or an inflammatory bowel disease. In patients who have suffered from a gastric or intestinal ulcer, it is possible that the likelihood of gastrointestinal bleeding increases. Tell your doctor.
• If you feel depressed or have thoughts of suicide, or if you notice unusual changes in your behavior, you should see your doctor.
• If you have an elevated Have intraocular pressure due to chronic wide-angle glaucoma. The dose of Lecapon-Mepha may need to be adjusted and your intraocular pressure monitored.
• If you are taking other medicines that can occasionally cause a drop in blood pressure (orthostatic hypotension), as Lecapon-Mepha can intensify such reactions. If involuntary movements occur or worsen after starting treatment with Lecapon-Mepha, you should consult your doctor, as the dosage of your medication may have to be adjusted.
• If If you notice severe muscle stiffness, severe muscle twitching, severe muscle pain or weakness, tremors, restlessness, confusion, fever, rapid heartbeat or large fluctuations in blood pressure, you should contact your doctor immediately.
• If you stop taking Lecapon-Mepha this should only be done in consultation with your doctor, as Lecapon-Mepha may be slowly discontinued and the dose of your other medicines may be reduced Parkinson's disease needs to be adjusted to avoid worsening Parkinson's symptoms or side effects.
• If you have increased diarrhea, you should check your body weight regularly; If you notice any noticeable weight loss, your doctor should be informed.
• If you develop progressive loss of appetite, exhaustion (asthenia) and weight loss within a relatively short period of time. A full medical evaluation should be considered in this case.
• If you, family members, or caregivers notice that you are developing addiction-like symptoms that lead to cravings, tell your doctor or health care professional Cans of Lecapon-Mepha and otherser medicines used to treat Parkinson's disease (known as dopamine dysregulation syndrome).
• If you, family members, or caregivers notice that you are developing an urge or desire to be in a If you behave in ways that are unusual for you, or if you cannot resist the urge, urge or urge to perform certain actions that may be harmful to you or others, talk to your doctor. Such behaviors are known as impulse control disorders and can include gambling addiction, eating or shopping addiction, abnormally increased sexual desire, or overuse of sexual thoughts or feelings. Your doctor may need to review your treatment.

Lecapon-Mepha may cause dizziness or mild headaches due to a drop in blood pressure. This can affect the ability to react, drive and use tools or machines.

In rare cases drowsiness and sudden sleep may occur during treatment. The latter can sometimes occur without warning or drowsiness. If you suddenly fall asleep or are very drowsy during the day, you must therefore not drive or engage in other activities (e.g. use tools or machines) while taking Lecapon-Mepha, in which reduced alertness endangers you or others. You should refrain from driving a vehicle, such as the activities mentioned above, until you have sufficient experience with the use of the drug and can rule out the possible occurrence of these impairments with sufficient certainty.

Taking other medicines:

Lecapon-Mepha can influence the effects and side effects of many other medicines. Conversely, the effects and side effects of Lecapon-Mepha can be influenced by other medicines.

It is particularly important that you tell your doctor which medicines (including those you bought yourself or herbal ones) you are currently using are taking or have recently taken.

An intensification of the effects and side effects of the following drugs by Lecapon-Mepha is possible with:

• Certain mood-enhancing drugs (antidepressants) of the tricyclic antidepressant type, MAO-A inhibitors, norepinephrine reuptake inhibitors (active ingredients such as maprotiline and venlafaxine).
• Medicinal products with the following active ingredients : Paroxetine, adrenaline, noradrenaline, dopamine, dobutamine, alpha-methyldopa and apomorphine.

The following drugs can reduce the effect of Lecapon-Mepha :

• Besti mmmed drugs used to treat psychosis or schizophrenia [e.g. Phenothiazines (e.g. active ingredients such as levomepromazine, thioridazine, fluphenazine) and butyrophenones (e.g. haloperidol)].
• Certain drugs used to treat nausea and vomiting (such as metoclopramide).
• As well as drugs for Prevention of seizures (epilepsy) with phenytoin and medicines containing papavarin.

Therefore, you must tell your doctor or health care professional if you are taking these medicines and / or if Lecapon- Notice Mepha.

Lecapon-Mepha can impair the absorption of iron through the gastrointestinal tract. Therefore, Lecapon-Mepha should be taken and iron-containing medicines should be taken at least 2-3 hours apart.

Please only take Lecapon-Mepha after consulting your doctor, if you know that you are intolerant to sugar.

Lecapon-Mepha 100/25/200 mg Lactab contains the azo dye Allura Red AC (E129) and Lecapon-Mepha 150 / 37.5 / 200 mg Lactab contains the Azo dye azorubine (E122). These can cause allergic reactions.

Tell your doctor or pharmacist if you

• suffer from other diseases,
• Have allergies or
• take or apply other medicines (including ones you have bought yourself!).

Can Lecapon-Mepha be taken during pregnancy or while breastfeeding?

Lecapon-Mepha must not be used during pregnancy. Women are not allowed to breastfeed during treatment with Lecapon-Mepha.

How do you use Lecapon-Mepha?

A Lactab Lecapon-Mepha contains one treatment dose each. Take only one Lactab Lecapon-Mepha at a time. You should not take 2 or more Lactab Lecapon-Mepha at one time. Do not share the lactab.

You should strictly follow your doctor's instructions when taking Lecapon-Mepha, other medicines containing levodopa, and other medicines for Parkinson's disease . This includes following the instructions on when and how to take your medicine.

Do not change the prescribed dosage on your own. If you think the medicine is too weak or too strong, talk to your doctor or pharmacist.

You should not start treatment with Lecapon-Mepha without extensive prior advice from your doctor Do not take Lecapon-Mepha together or shortly before or after a very protein-rich meal (e.g. lots of meat, fish, cheese and eggs), as the intake of one Active ingredient of Lecapon-Mepha can be impaired. Lecapon-Mepha and iron supplements should be taken at least 2-3 hours apart.

If you accidentally take too much Lactab Lecapon-Mepha, you should contact your doctor or pharmacist immediately or speak to a pharmacist.

As soon as you realize that you have forgotten to take Lecapon-Mepha, you should do so. However, two Lactab Lecapon-Mepha should not be taken within the same hour. You should also not take a double dose to make up for a forgotten single dose. You should then resume your usual dosage regimen.

The use and safety of Lecapon-Mepha in children and adolescents under 18 years of age has not been tested. No data is available. Lecapon-Mepha must not be taken by children and adolescents.

What else should you watch out for?

The medicinal product may only be used up to the date marked «EXP» on the container.

Storage information

Store in the original packaging and not above 25 ° C. Keep out of the reach of children.

Further information

Your doctor or pharmacist can provide you with further information. These persons have the detailed specialist information at their disposal.

What does Lecapon-Mepha contain?

Active ingredients

Lecapon-Mepha 50 mg / 12.5 mg / 200 mg, Lactab : 50 mg levodopa, 12.5 mg carbidopa, 200 mg entacapone.

Lecapon-Mepha 75 mg / 18.75 mg / 200 mg, lactab : 75 mg levodopa, 18.75 mg carbidopa, 200 mg entacapone. Lecapon-Mepha 100 mg / 25 mg / 200 mg, Lactab : 100 mg levodopa, 25 mg carbidopa, 200 mg entacapone.

Lecapon-Mepha 125 mg / 31.25 mg / 200 mg, Lactab : 125 mg levodopa, 31.25 mg carbidopa, 200 mg entacapone.

Lecapon-Mepha 150 mg / 37.5 mg / 200 mg, lactab : 150 mg levodopa, 37.5 mg carbidopa, 200 mg entacapone.

Lecapon-Mepha 200 mg / 50 mg / 200 mg, lactab : 200 mg levodopa, 50 mg carbidopa, 200 mg entacapone.

Excipients

Tablet core (all dose strengths):

Microcrystalline e Cellulose, lactose, low-substituted hydroxypropyl cellulose, povidone, highly dispersed silicon dioxide, magnesium stearate.

Tablet film:

Lecapon-Mepha 50 mg / 12.5 mg / 200 mg: titanium dioxide (E171), hypromellose, Glycerol, polysorbate 80, magnesium stearate, iron oxide yellow (E172), iron oxide red (E172), iron oxide black (E172).

Lecapon-Mepha 75 mg / 18.75 mg / 200 mg: Titanium dioxide (E171), hypromellose, glycerol, polysorbate 80, magnesium stearate, yellow iron oxide (E172), red iron oxide (E172).